Setrusumab (BPS804)
For the treatment of Osteogenesis Imperfecta (“OI”)
Our pipeline
At Mereo, we unlock the potential of rare disease and tumor therapies that were not being progressed in pharmaceutical or biotechnology companies – creating new possibilities for all our stakeholders, from our investors to the patients that need us most.
Our pipeline currently consists of six clinical-stage product candidates.
Core programs
We have already delivered three successful Phase 2 studies with a Phase 2 and Phase 1b/2 ongoing.
Core programs
Partnered and Partnering Opportunities on Non-Core Programs
We have two additional programs with current partnering opportunities. Navicixizumab has been licensed out to OncXerna.
Navicixizumab (OMP305B83)
For the treatment of platinum-resistant ovarian cancer. Navicixizumab has been partnered with OncXerna Therapeutics Inc. for further development.
Acumapimod (BCT197)
For the treatment of acute exacerbations of chronic obstructive pulmonary disease (“AECOPD”).
Leflutrozole (BGS649)
For the treatment of male infertility associated with hypogonadotropic hypogonadism (“HH”).
Partnered and partnering opportunities on non-core programs
Pipeline News
Mereo BioPharma To Present Data Update for the Phase 1b/2 Study (ACTIVATE) of Etigilimab and Nivolumab at 2022 ASCO Annual Meeting; Mereo Also Updates Capital Allocation and Portfolio Prioritization Plan
02 June 2022Mereo BioPharma today announced updated clinical data from its open-label Phase 1b/2 Study of Etigilimab and Nivolumab in subjects with Select Locally Advanced or Metastatic Solid Tumors (ACTIVATE). The data will be presented in a poster session at the 2022 American Society of Clinical Oncology (ASCO) Annual Meeting on June 5, 2022. The Company also provided an update on its capital allocation and portfolio prioritization plan.
Mereo BioPharma Announces the Presentation of Updated Data From a Phase 1b/2 Study of Etigilimab as a Poster at the 2022 American Society of Clinical Oncology Annual Meeting
26 May 2022Mereo BioPharma today announced the presentation of interim clinical data from its Phase 1b/2 Study of Etigilimab and Nivolumab in Subjects with Select Locally Advanced or Metastatic Solid Tumors in a poster at the 2022 American Society of Clinical Oncology (ASCO) Annual Meeting taking place June 3 – 7, 2022 in Chicago IL.
Mereo BioPharma announces Positive Top-Line Efficacy and Safety Data from “ASTRAEUS” Phase 2 Trial of Alvelestat in Alpha-1 Antitrypsin Deficiency- associated Emphysema
09 May 2022Mereo BioPharma announces positive topline results from ASTRAEUS a Phase 2 trial of alvelestat in Alpha-1 Antitrypsin Deficiency- associated Emphysema.
Mereo BioPharma to Host Conference Call Highlighting Top-line Clinical Data from “ASTRAEUS” Phase 2 Study of Alvelestat
06 May 2022Mereo BioPharma Group plc today announced it will host a conference call on Monday, May 9, 2022 at 10:30 a.m. ET to review top-line clinical data from its “ASTRAEUS” Phase 2 Study of Alvelestat in Alpha-1 Antitrypsin Deficiency-associated Emphysema.