We are currently completing a Phase 1a/b clinical trial in patients with advanced or metastatic solid tumors. The Phase 1a portion investigated single agent activity with the Phase 1b in combination with nivolumab. Etigilimab is an anti-TIGIT therapeutic candidate designed to activate the immune system through multiple mechanisms and enable anti-tumor activity. TIGIT (T-cell immunoreceptor with Ig and ITIM domains) is an inhibitory receptor that is thought to prevent T-cells from attacking tumor cells, similar to the inhibitory protein PD-1.

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Information on OncoMed's anti-TIGIT clinical program is available here: OMP-313M32 ClinicalTrials.gov.

Public presentations of data from OncoMed's anti-TIGIT program include:

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