The following shareholders hold in excess of 3% or more of the Company’s issued share capital (PROFORMA):

09 July 2020

Institutional Shareholder Number of Shares  % of Issued Share Capital
Vivo Capital, LLC 37,422,681 11.05%
OrbiMed Advisors LLC 33,532,681 9.90%
Baker Bros. Advisors LP 33,532,681 9.90%
Boxer Capital, LLC 33,532,681 9.90%
Aspire Capital Fund, LLC 23,528,332 6.95%
Surveyor Capital Ltd 20,773,822 6.13%
Pontifax Venture Capital 17,311,513 5.11%
Samsara BioCapital, L.P 16,157,415 4.77%
Novartis Pharma AG 15,703,871 4.64%
Commodore Capital Master, L.P 12,695,116 3.75%

 The Directors hold the following shareholding interest in the company: 

Directors  Number of Shares* % of Issued Share Capital
Kunal Kashyap 1,497,735 0.44%
Deepa Pakianathan** 1,283,670 0.38%
Denise Scots-Knight 929,699 0.27%
Peter Bains 206,796 0.06%
Anders Ekblom 189,702 0.06%
Peter Fellner 65,500 0.02%
Paul Blackburn 22,624 0.01%

* ordinary shares figures include ordinary shares represented by ADSs
** as a General Partner of Delphi Ventures

Issued share capital 338,713,962

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